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COMPOSITION: Each tablet contains Cefixime 200mg & Ofloxacin 200mg
INTRODUCTION: Cefixime is an orally strong 3rd generation cephalosporin that employs its bactericidal action against both gram negative and gram-positive organisms by hindering bacterial cell wall fusion. It is exceedingly active in contrast to enterobacteriaceae, Streptococcus pyogenes, Haemophilus influenzae, & Streptococcus pneumoniae & numerous beta-lactamase creating bacteria. Ofloxacin is a bactericidal medicine. It acts by constraining the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4. DNA gyrase aids in the development of an extremely condensed three-dimensional structure of the DNA through its closing and nicking action and also by presenting negative supercoil into the DNA double helix. Ofloxacin constrains DNA gyrase which causes abnormal linkage amid opened DNA and gyrase and negative supercoiling is also decreased. This will constrain transformation of DNA into RNA and consequent protein synthesis.
Cefi-O is specified for the cure of the following infections:
DOSAGE & ADMINISTRATION: To be sold only by retail on the prescription of a Reputed Medical Practitioner only. The dosage is as given by the physician.
PRESENTATION: 10 strips each of 10 tablets each in a carton